The station began operation on September 15, 1986 as WTWS. It was owned by R & R Media and ran a general entertainment format.
In 1990, the station began to take programming that WTXX chose not to renew. The station had added more infomercials by 1993. It was sold to Paxson in 1994 and rights to its programming were acquired by LIN Television.
Under Paxson, WTWS ran religious programming in the morning, infomercials in the afternoon and evenings, and worship programming overnight. Paxson then bought WHCT in 1997, and sold WTWS to Roberts Broadcasting.
Paxson, however, sold WHCT to Entravision in 1998, and affiliated with WTWS. The station became a Pax affiliate that year, and changed its call letters to WHPX to reflect its affiliation. In 2005, Paxson repurchased channel 26.
February 17, 2009 WHPX shut down its analog signal, continuing to broadcast on channel 26 in DTV mode.